Children at Risk
The age of onset of CD is critical. The earlier the age of onset, the worse the prognosis.
Early onset CD, which occurs before adolescence, is the most common.
Late-onset CD occurs after early adolescence. The prevalence of CD has increased over recent decades and is higher in urban than in rural settings. It is estimated that six percent of all children have CD, with a male-female ratio of four to one. Aggressive children comprise one-third to one-half of the referrals to child and adolescent clinics.